GC36807
ON 146040
Also known as (7Z)-2-[4-(4-methylpiperazin-1-yl)anilino]-7-[(4-nitrophenyl)methylidene]-5H-pyrimido[4,5-b][1,4]thiazin-6-one
ON 146040 is a potent PI3Kα and PI3Kδ (IC50≈14 and 20 nM, respectively) inhibitor· ON 146040 also inhibits Abl1 (IC50＜150 nM)
ChemicalCAS1404231-34-0MW489.55FormulaC24H23N7O3S
- CAS number
- 1404231-34-0
- Molecular weight
- 489.55
- Formula
- C24H23N7O3S
- Solubility
- Soluble in DMSO
- InChIKey
- PKCHFYZACODWAI-STZFKDTASA-N
- Catalogue number
- GC36807
- Brand
- GLPBIO
Computed properties PubChem CID 73297262 · XLogP 3.8 · TPSA 145 Ų · H-bond donors 2
- XLogP
- 3.8
- TPSA
- 145 Ų
- H-bond donors
- 2
- H-bond acceptors
- 9
- Rotatable bonds
- 4
- Heavy atoms
- 35
SMILES CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C4C(=N3)S/C(=C\C5=CC=C(C=C5)[N+](=O)[O-])/C(=O)N4
Computed descriptors from PubChem (CID 73297262), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il