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Chemical structure of Sigma-1 receptor antagonist 3

GC38048

Sigma-1 receptor antagonist 3

Also known as 5-chloro-2-(4-fluorophenyl)-4-methyl-6-(3-piperidin-1-ylpropoxy)pyrimidine

Sigma-1 receptor antagonist 3 (compound135) is a potent and selective Sigma-1 (σ1) receptor antagonist with a Ki of 1·14 nM

ChemicalCAS1639220-17-9MW363.86FormulaC19H23ClFN3O
CAS number
1639220-17-9
Molecular weight
363.86
Formula
C19H23ClFN3O
Solubility
DMSO: 12·5 mg/mL (34·35 mM)
InChIKey
OAIHSWLLDNASTO-UHFFFAOYSA-N
Catalogue number
GC38048
Brand
GLPBIO
Computed properties PubChem CID 118723363 · XLogP 4.5 · TPSA 38.3 Ų · H-bond donors 0
XLogP
4.5
TPSA
38.3 Ų
H-bond donors
0
H-bond acceptors
5
Rotatable bonds
6
Heavy atoms
25

SMILES CC1=C(C(=NC(=N1)C2=CC=C(C=C2)F)OCCCN3CCCCC3)Cl

Computed descriptors from PubChem (CID 118723363), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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