Loading...
Chemical structure of Sigma-1 receptor antagonist 1

GC38038

Sigma-1 receptor antagonist 1

Also known as 5-chloro-2-(4-chlorophenyl)-4-methyl-6-(3-piperidin-1-ylpropoxy)pyrimidine

Sigma?1 receptor antagonist 1 (compound 137) is a potent and selective sigma-1 receptor (σ1R) antagonist, with a high binding affinity to σ1R receptor (Ki = 1·06 nM)

ChemicalCAS1639220-19-1MW380.31FormulaC19H23Cl2N3O
CAS number
1639220-19-1
Molecular weight
380.31
Formula
C19H23Cl2N3O
Solubility
DMSO： 6·25 mg/mL (16·43 mM)
InChIKey
MSFUOAXHQLXDAO-UHFFFAOYSA-N
Catalogue number
GC38038
Brand
GLPBIO
Computed properties PubChem CID 101910737 · XLogP 5.1 · TPSA 38.3 Ų · H-bond donors 0
XLogP
5.1
TPSA
38.3 Ų
H-bond donors
0
H-bond acceptors
4
Rotatable bonds
6
Heavy atoms
25

SMILES CC1=C(C(=NC(=N1)C2=CC=C(C=C2)Cl)OCCCN3CCCCC3)Cl

Computed descriptors from PubChem (CID 101910737), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.