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Chemical structure of Sigma-1 receptor antagonist 2

GC38039

Sigma-1 receptor antagonist 2

Also known as 5-chloro-2-(4-methoxyphenyl)-4-methyl-6-(3-piperidin-1-ylpropoxy)pyrimidine

Sigma-1 receptor antagonist 2 is a potent and selective sigma 1 receptor (σ1 R) antagonist with Kis of 3·88 and 1288 nM for σ1 and σ2 receptor, respectively

ChemicalCAS1639220-15-7MW375.89FormulaC20H26ClN3O2
CAS number
1639220-15-7
Molecular weight
375.89
Formula
C20H26ClN3O2
Solubility
DMSO: 86·67 mg/mL (230·57 mM)
InChIKey
FAEOHCOAHZFOEX-UHFFFAOYSA-N
Catalogue number
GC38039
Brand
GLPBIO
Computed properties PubChem CID 118723361 · XLogP 4.4 · TPSA 47.5 Ų · H-bond donors 0
XLogP
4.4
TPSA
47.5 Ų
H-bond donors
0
H-bond acceptors
5
Rotatable bonds
7
Heavy atoms
26

SMILES CC1=C(C(=NC(=N1)C2=CC=C(C=C2)OC)OCCCN3CCCCC3)Cl

Computed descriptors from PubChem (CID 118723361), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
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