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Chemical structure of SRT 1720

GC37677

SRT 1720

Also known as N-[2-[3-(piperazin-1-ylmethyl)imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]quinoxaline-2-carboxamide

SRT 1720 is a selective activator of human SIRT1 with an EC1·5 of 0·16 μM, and shows less potent activities for SIRT2 and SIRT3 with EC1·5s of 37 μM and > 300 μM, respectively

ChemicalCAS925434-55-5MW469.56FormulaC25H23N7OS
CAS number
925434-55-5
Molecular weight
469.56
Formula
C25H23N7OS
Solubility
DMSO : 62·5 mg/mL (133·10 mM; ultrasonic and adjust pH to 5 with HCl)
InChIKey
IASPBORHOMBZMY-UHFFFAOYSA-N
Catalogue number
GC37677
Brand
GLPBIO
Computed properties PubChem CID 24180125 · XLogP 3.2 · TPSA 116 Ų · H-bond donors 2
XLogP
3.2
TPSA
116 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
5
Heavy atoms
34

SMILES C1CN(CCN1)CC2=CSC3=NC(=CN23)C4=CC=CC=C4NC(=O)C5=NC6=CC=CC=C6N=C5

Computed descriptors from PubChem (CID 24180125), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.