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Chemical structure of SIS17

GC37643

SIS17

Also known as N'-hexadecylthiophene-2-carbohydrazide

SIS17 is a mammalian histone deacetylase 11 (HDAC 11) inhibitor with an IC50 value of 0·83 μM, inhibits the demyristoylation HDAC11 substrate, serine hydroxymethyl transferase 2, without inhibiting other HDACs

ChemicalCAS2374313-54-7MW366.6FormulaC21H38N2OS
CAS number
2374313-54-7
Molecular weight
366.6
Formula
C21H38N2OS
Solubility
DMSO: 125 mg/mL (340·97 mM)
InChIKey
HSHXDCVZWHOWCS-UHFFFAOYSA-N
Catalogue number
GC37643
Brand
GLPBIO
Computed properties PubChem CID 139035087 · XLogP 8.7 · TPSA 69.4 Ų · H-bond donors 2
XLogP
8.7
TPSA
69.4 Ų
H-bond donors
2
H-bond acceptors
3
Rotatable bonds
17
Heavy atoms
25

SMILES CCCCCCCCCCCCCCCCNNC(=O)C1=CC=CS1

Computed descriptors from PubChem (CID 139035087), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.