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Chemical structure of SIRT7 inhibitor 97491

GC60338

SIRT7 inhibitor 97491

Also known as 3-N-[5-(4-chlorophenyl)-1,3-oxazol-2-yl]benzene-1,3-diamine

SIRT7 inhibitor 97491 is a potent SIRT 7 inhibitor that reduces the deacetylase activity of SIRT7 in a dose-dependent manner with an IC50 of 325 nM

ChemicalCAS1807758-81-1MW285.73FormulaC15H12ClN3O
CAS number
1807758-81-1
Molecular weight
285.73
Formula
C15H12ClN3O
Solubility
DMSO :57 mg/mL(199·48 mM; Moisture absorption of DMSO will reduce the solubility of the compound, please use newly opened DMSO)
InChIKey
RMRVZWMKRCLSFX-UHFFFAOYSA-N
Catalogue number
GC60338
Brand
GLPBIO
Computed properties PubChem CID 146018038 · XLogP 3.8 · TPSA 64.1 Ų · H-bond donors 2
XLogP
3.8
TPSA
64.1 Ų
H-bond donors
2
H-bond acceptors
4
Rotatable bonds
3
Heavy atoms
20

SMILES C1=CC(=CC(=C1)NC2=NC=C(O2)C3=CC=C(C=C3)Cl)N

Computed descriptors from PubChem (CID 146018038), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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Lead time
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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