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Chemical structure of EPZ020411 hydrochloride

GC36000

EPZ020411 hydrochloride

Also known as N,N'-dimethyl-N'-[[5-[4-[3-[2-(oxan-4-yl)ethoxy]cyclobutyl]oxyphenyl]-1H-pyrazol-4-yl]methyl]ethane-1,2-diamine;hydrochloride

EPZ020411 hydrochloride is a selective inhibitor of PRMT6 with an IC50 of 10 nM, it has >10 folds selectivity for PRMT6 over PRMT1 and PRMT8· EPZ020411 hydrochloride can be used for the research of cancer

ChemicalCAS2070015-25-5MW479.06FormulaC25H39ClN4O3
CAS number
2070015-25-5
Molecular weight
479.06
Formula
C25H39ClN4O3
Solubility
DMSO: 50 mg/mL (104·37 mM); Water: ≥ 41 mg/mL (85·58 mM)
InChIKey
LIDZHJMYAKPGOJ-UHFFFAOYSA-N
Catalogue number
GC36000
Brand
GLPBIO
Computed properties PubChem CID 119081410 · TPSA 71.6 Ų · H-bond donors 3 · H-bond acceptors 6
TPSA
71.6 Ų
H-bond donors
3
H-bond acceptors
6
Rotatable bonds
12
Heavy atoms
33

SMILES CNCCN(C)CC1=C(NN=C1)C2=CC=C(C=C2)OC3CC(C3)OCCC4CCOCC4.Cl

Computed descriptors from PubChem (CID 119081410), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.