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Chemical structure of EPZ5676

GC12932

EPZ5676

Also known as (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-[[[3-[2-(6-tert-butyl-1H-benzimidazol-2-yl)ethyl]cyclobutyl]-propan-2-ylamino]methyl]oxolane-3,4-diol

A highly potent DOT1L inhibitor

ChemicalCAS1380288-87-8MW562.71FormulaC30H42N8O3
CAS number
1380288-87-8
Molecular weight
562.71
Formula
C30H42N8O3
Solubility
≥ 28·15 mg/mL in DMSO, ≥ 50·3 mg/mL in EtOH with ultrasonic
InChIKey
LXFOLMYKSYSZQS-XKHGBIBOSA-N
Catalogue number
GC12932
Brand
GLPBIO
Computed properties PubChem CID 57345410 · XLogP 4.3 · TPSA 151 Ų · H-bond donors 4
XLogP
4.3
TPSA
151 Ų
H-bond donors
4
H-bond acceptors
9
Rotatable bonds
9
Heavy atoms
41

SMILES CC(C)N(C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O)C4CC(C4)CCC5=NC6=C(N5)C=C(C=C6)C(C)(C)C

Computed descriptors from PubChem (CID 57345410), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.