Loading...
Chemical structure of E3 ligase Ligand 16

GC35930

E3 ligase Ligand 16

Also known as 2-[4-[(4S,5R)-4,5-bis(4-chlorophenyl)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-dihydroimidazole-1-carbonyl]-2-oxopiperazin-1-yl]acetic acid

E3 ligase Ligand 16 (MDM2 ligand 1) is the Nutlin 3-based MDM2 ligand· E3 ligase Ligand 16 can be connected to the ligand for protein by a linker to form PROTAC

ChemicalCAS2249750-27-2MW639.53FormulaC32H32Cl2N4O6
CAS number
2249750-27-2
Molecular weight
639.53
Formula
C32H32Cl2N4O6
Solubility
Soluble in DMSO
InChIKey
CYFZSMNCDNFMOG-XZWHSSHBSA-N
Catalogue number
GC35930
Brand
GLPBIO
Computed properties PubChem CID 138576186 · XLogP 5 · TPSA 112 Ų · H-bond donors 1
XLogP
5
TPSA
112 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
8
Heavy atoms
44

SMILES CC(C)OC1=C(C=CC(=C1)OC)C2=N[C@H]([C@H](N2C(=O)N3CCN(C(=O)C3)CC(=O)O)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl

Computed descriptors from PubChem (CID 138576186), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.