GC30164
E3 ligase Ligand 4
Also known as 2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindole-1,3-dione
E3 ligase Ligand 4 (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein· E3 ligase Ligand 4 (Cereblon ligand 4) can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1
ChemicalCAS835616-60-9MW276.22FormulaC13H9FN2O4
- CAS number
- 835616-60-9
- Molecular weight
- 276.22
- Formula
- C13H9FN2O4
- Solubility
- DMSO ： 200 mg/mL (724·06 mM)
- InChIKey
- CRAUTELYXAAAPW-UHFFFAOYSA-N
- Catalogue number
- GC30164
- Brand
- GLPBIO
Computed properties PubChem CID 11859051 · XLogP 0.4 · TPSA 83.6 Ų · H-bond donors 1
- XLogP
- 0.4
- TPSA
- 83.6 Ų
- H-bond donors
- 1
- H-bond acceptors
- 5
- Rotatable bonds
- 1
- Heavy atoms
- 20
SMILES C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)F
Computed descriptors from PubChem (CID 11859051), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il