GC32848
E3 ligase Ligand 2
Also known as 2-(2,6-dioxopiperidin-3-yl)-4-hydroxyisoindole-1,3-dione
E3 ligase Ligand 2 (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein· E3 ligase Ligand 2 (Cereblon ligand 2) can be connected to the ligand for protein by a linker to form PROTACs
ChemicalCAS5054-59-1MW274.23FormulaC13H10N2O5
- CAS number
- 5054-59-1
- Molecular weight
- 274.23
- Formula
- C13H10N2O5
- Solubility
- DMSO ： ≥ 36·5 mg/mL (133·10 mM)
- InChIKey
- XMPJICVFSDYOEG-UHFFFAOYSA-N
- Catalogue number
- GC32848
- Brand
- GLPBIO
Computed properties PubChem CID 11778087 · XLogP 0.5 · TPSA 104 Ų · H-bond donors 2
- XLogP
- 0.5
- TPSA
- 104 Ų
- H-bond donors
- 2
- H-bond acceptors
- 5
- Rotatable bonds
- 1
- Heavy atoms
- 20
SMILES C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)O
Computed descriptors from PubChem (CID 11778087), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il