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Chemical structure of AMG2850

GC35316

AMG2850

Also known as (8R)-8-[4-(trifluoromethyl)phenyl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]-6,8-dihydro-5H-1,7-naphthyridine-7-carboxamide

AMG2850 is a potent, orally bioavailable and selective transient receptor potential melastatin 8 (TRPM8) antagonist

ChemicalCAS1470018-52-0MW417.35FormulaC19H17F6N3O
CAS number
1470018-52-0
Molecular weight
417.35
Formula
C19H17F6N3O
Solubility
DMSO ： 100 mg/mL (239·61 mM; Need ultrasonic)
InChIKey
DDBWYSSPWMXBIY-MEDUHNTESA-N
Catalogue number
GC35316
Brand
GLPBIO
Computed properties PubChem CID 90655362 · XLogP 4.2 · TPSA 45.2 Ų · H-bond donors 1
XLogP
4.2
TPSA
45.2 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
2
Heavy atoms
29

SMILES C[C@@H](C(F)(F)F)NC(=O)N1CCC2=C([C@H]1C3=CC=C(C=C3)C(F)(F)F)N=CC=C2

Computed descriptors from PubChem (CID 90655362), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.