GC34127
GDC-0575 dihydrochloride
Also listed as GDC-0575 dihydrochloride (ARRY-575 dihydrochloride)
GDC-0575 dihydrochloride (ARRY-575 dihydrochloride) (ARRY-575 dihydrochloride) is an orally bioavailable CHK1 inhibitor, with an IC50 of 1·2 nM, and has antitumor activity
ChemicalCAS1657014-42-0MW451.19FormulaC16H22BrCl2N5O
- CAS number
- 1657014-42-0
- Molecular weight
- 451.19
- Formula
- C16H22BrCl2N5O
- Solubility
- DMSO ： 65 mg/mL (144·06 mM)
- InChIKey
- OYMHZTORKRPOBI-YQFADDPSSA-N
- Catalogue number
- GC34127
- Brand
- GLPBIO
Computed properties PubChem CID 131749450 · TPSA 87 Ų · H-bond donors 5 · H-bond acceptors 4
- TPSA
- 87 Ų
- H-bond donors
- 5
- H-bond acceptors
- 4
- Rotatable bonds
- 3
- Heavy atoms
- 25
SMILES C1C[C@H](CN(C1)C2=C3C(=CNC3=NC=C2Br)NC(=O)C4CC4)N.Cl.Cl
Computed descriptors from PubChem (CID 131749450), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il