GC32885
GDC-0575 (ARRY-575, RG7741)
Also known as N-[4-[(3R)-3-aminopiperidin-1-yl]-5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl]cyclopropanecarboxamide
GDC-0575 (ARRY-575, RG7741) (ARRY-575, RG7741) is a highly-selective oral small-molecule Chk1 inhibitor with an IC50 of 1·2nM
ChemicalCAS1196541-47-5MW378.27FormulaC16H20BrN5O
- CAS number
- 1196541-47-5
- Molecular weight
- 378.27
- Formula
- C16H20BrN5O
- Solubility
- DMSO ： ≥ 50 mg/mL (132·18 mM)
- InChIKey
- BAZRWWGASYWYGB-SNVBAGLBSA-N
- Catalogue number
- GC32885
- Brand
- GLPBIO
Computed properties PubChem CID 46917793 · XLogP 1.4 · TPSA 87 Ų · H-bond donors 3
- XLogP
- 1.4
- TPSA
- 87 Ų
- H-bond donors
- 3
- H-bond acceptors
- 4
- Rotatable bonds
- 3
- Heavy atoms
- 23
SMILES C1C[C@H](CN(C1)C2=C3C(=CNC3=NC=C2Br)NC(=O)C4CC4)N
Computed descriptors from PubChem (CID 46917793), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il