Loading...
Chemical structure of GDC-0276

GC39559

GDC-0276

Also known as 4-(1-adamantylmethoxy)-N-(azetidin-1-ylsulfonyl)-5-cyclopropyl-2-fluorobenzamide

GDC-0276 is a potent, selective, reversible, orally active voltage-gated sodium channel 1·7 (NaV1·7) inhibitor with an IC50 value of 0·4nM

ChemicalCAS1494581-70-2MW462.58FormulaC24H31FN2O4S
CAS number
1494581-70-2
Molecular weight
462.58
Formula
C24H31FN2O4S
Solubility
DMSO： 125 mg/mL (270·22 mM)
InChIKey
PTCBNPULJWGSML-UHFFFAOYSA-N
Catalogue number
GC39559
Brand
GLPBIO
Computed properties PubChem CID 91809347 · XLogP 4.7 · TPSA 84.1 Ų · H-bond donors 1
XLogP
4.7
TPSA
84.1 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
7
Heavy atoms
32

SMILES C1CN(C1)S(=O)(=O)NC(=O)C2=C(C=C(C(=C2)C3CC3)OCC45CC6CC(C4)CC(C6)C5)F

Computed descriptors from PubChem (CID 91809347), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.