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Chemical structure of MK-0429 (L-000845704)

GC32055

MK-0429 (L-000845704)

Also known as (3S)-3-(6-methoxy-3-pyridinyl)-3-[2-oxo-3-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]imidazolidin-1-yl]propanoic acid

MK-0429 (L-000845704) (L-000845704) is an orally active, potent, selective and nonpeptide pan-integrin antagonist with IC50 values of 1·6 nM, 2·8 nM, 0·1 nM, 0·7 nM, 0·5 nM and 12·2 nM for αvβ1, αvβ3, αvβ5, αvβ6, αvβ8 and α5β1, respectively

ChemicalCAS227963-15-7MW439.51FormulaC23H29N5O4
CAS number
227963-15-7
Molecular weight
439.51
Formula
C23H29N5O4
Solubility
DMSO : 250 mg/mL (568·82 mM)
InChIKey
HGFOOLONGOBCMP-IBGZPJMESA-N
Catalogue number
GC32055
Brand
GLPBIO
Computed properties PubChem CID 9853559 · XLogP 1.8 · TPSA 108 Ų · H-bond donors 2
XLogP
1.8
TPSA
108 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
9
Heavy atoms
32

SMILES COC1=NC=C(C=C1)[C@H](CC(=O)O)N2CCN(C2=O)CCCC3=NC4=C(CCCN4)C=C3

Computed descriptors from PubChem (CID 9853559), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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