GC31881
MS417 (GTPL7512)
Also known as methyl 2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetate
MS417 (GTPL7512) is a selective BET-specific BRD4 inhibitor, binds to BRD4-BD1 and BRD4-BD2 with IC50s of 30, 46 nM and Kds of 36·1, 25·4 nM, respectively, with weak selectivity at CBP BRD (IC50, 32·7 μM)
ChemicalCAS916489-36-6MW414.91FormulaC20H19ClN4O2S
- CAS number
- 916489-36-6
- Molecular weight
- 414.91
- Formula
- C20H19ClN4O2S
- Solubility
- Ethanol ： 50 mg/mL (120·51 mM)
- InChIKey
- GGRCIHACOIMRKY-HNNXBMFYSA-N
- Catalogue number
- GC31881
- Brand
- GLPBIO
Computed properties PubChem CID 59190723 · XLogP 3.9 · TPSA 97.6 Ų · H-bond donors 0
- XLogP
- 3.9
- TPSA
- 97.6 Ų
- H-bond donors
- 0
- H-bond acceptors
- 6
- Rotatable bonds
- 4
- Heavy atoms
- 28
SMILES CC1=C(SC2=C1C(=N[C@H](C3=NN=C(N32)C)CC(=O)OC)C4=CC=C(C=C4)Cl)C
Computed descriptors from PubChem (CID 59190723), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il