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Chemical structure of MK-5046

GC19413

MK-5046

Also known as (2S)-1,1,1-trifluoro-2-(4-pyrazol-1-ylphenyl)-3-[5-[[1-(trifluoromethyl)cyclopropyl]methyl]-1H-imidazol-2-yl]propan-2-ol

MK-5046 is a novel BRS-3 agonist, binds to BRS-3 with high affinity (mouse Ki = 1·6 nM, human Ki = 25 nM)

ChemicalCAS1022152-70-0MW444.37FormulaC20H18F6N4O
CAS number
1022152-70-0
Molecular weight
444.37
Formula
C20H18F6N4O
Solubility
Soluble in DMSO
InChIKey
UJINBEQCDMOAHM-SFHVURJKSA-N
Catalogue number
GC19413
Brand
GLPBIO
Computed properties PubChem CID 49871766 · XLogP 4.1 · TPSA 66.7 Ų · H-bond donors 2
XLogP
4.1
TPSA
66.7 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
6
Heavy atoms
31

SMILES C1CC1(CC2=CN=C(N2)C[C@](C3=CC=C(C=C3)N4C=CC=N4)(C(F)(F)F)O)C(F)(F)F

Computed descriptors from PubChem (CID 49871766), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.