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Chemical structure of MK-5108 (VX-689)

GC17162

MK-5108 (VX-689)

Also known as 4-(3-chloro-2-fluorophenoxy)-1-[[6-(1,3-thiazol-2-ylamino)-2-pyridinyl]methyl]cyclohexane-1-carboxylic acid

A potent inhibitor of Aurora kinases

ChemicalCAS1010085-13-8MW461.94FormulaC22H21ClFN3O3S
CAS number
1010085-13-8
Molecular weight
461.94
Formula
C22H21ClFN3O3S
Solubility
≥ 23·1 mg/mL in DMSO
InChIKey
LCVIRAZGMYMNNT-UHFFFAOYSA-N
Catalogue number
GC17162
Brand
GLPBIO
Computed properties PubChem CID 24748204 · XLogP 5.4 · TPSA 113 Ų · H-bond donors 2
XLogP
5.4
TPSA
113 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
7
Heavy atoms
31

SMILES C1CC(CCC1OC2=C(C(=CC=C2)Cl)F)(CC3=NC(=CC=C3)NC4=NC=CS4)C(=O)O

Computed descriptors from PubChem (CID 24748204), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.