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Chemical structure of PF-562271

GC15380

PF-562271

Also known as N-methyl-N-[3-[[[2-[(2-oxo-1,3-dihydroindol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]methyl]-2-pyridinyl]methanesulfonamide

PF-562271 is a potent small-molecule inhibitor of focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (Pyk2) with a IC50 of 1·5 and 14nmol/L, respectively

ChemicalCAS717907-75-0MW507.49FormulaC21H20F3N7O3S
CAS number
717907-75-0
Molecular weight
507.49
Formula
C21H20F3N7O3S
Solubility
≥ 25·35mg/mL in DMSO, ≥ 2·25 mg/mL in EtOH with ultrasonic and warming
InChIKey
MZDKLVOWGIOKTN-UHFFFAOYSA-N
Catalogue number
GC15380
Brand
GLPBIO
Computed properties PubChem CID 11713159 · XLogP 2 · TPSA 138 Ų · H-bond donors 3
XLogP
2
TPSA
138 Ų
H-bond donors
3
H-bond acceptors
12
Rotatable bonds
7
Heavy atoms
35

SMILES CN(C1=C(C=CC=N1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)C4)S(=O)(=O)C

Computed descriptors from PubChem (CID 11713159), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.