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Chemical structure of PF-562271 HCl

GC10810

PF-562271 HCl

Also known as N-methyl-N-[3-[[[2-[(2-oxo-1,3-dihydroindol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]methyl]-2-pyridinyl]methanesulfonamide;hydrochloride

PF-562271 (VS-6062) hydrochloride is a potent, ATP-competitive and reversible FAK and Pyk2 kinase inhibitor with IC50s of 1·5 nM and 13 nM, respectively

ChemicalCAS939791-41-0MW543.95FormulaC21H21ClF3N7O3S
CAS number
939791-41-0
Molecular weight
543.95
Formula
C21H21ClF3N7O3S
Solubility
≥ 26·35mg/mL in DMSO with gentle warming
InChIKey
RQEBZJWSAAWCAV-UHFFFAOYSA-N
Catalogue number
GC10810
Brand
GLPBIO
Computed properties PubChem CID 16222312 · TPSA 138 Ų · H-bond donors 4 · H-bond acceptors 12
TPSA
138 Ų
H-bond donors
4
H-bond acceptors
12
Rotatable bonds
7
Heavy atoms
36

SMILES CN(C1=C(C=CC=N1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)C4)S(=O)(=O)C.Cl

Computed descriptors from PubChem (CID 16222312), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.