
GC10810
PF-562271 HCl
Also known as N-methyl-N-[3-[[[2-[(2-oxo-1,3-dihydroindol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]methyl]-2-pyridinyl]methanesulfonamide;hydrochloride
PF-562271 (VS-6062) hydrochloride is a potent, ATP-competitive and reversible FAK and Pyk2 kinase inhibitor with IC50s of 1·5 nM and 13 nM, respectively
ChemicalCAS939791-41-0MW543.95FormulaC21H21ClF3N7O3S
- CAS number
- 939791-41-0
- Molecular weight
- 543.95
- Formula
- C21H21ClF3N7O3S
- Solubility
- ≥ 26·35mg/mL in DMSO with gentle warming
- InChIKey
- RQEBZJWSAAWCAV-UHFFFAOYSA-N
- Catalogue number
- GC10810
- Brand
- GLPBIO
Computed properties PubChem CID 16222312 · TPSA 138 Ų · H-bond donors 4 · H-bond acceptors 12
- TPSA
- 138 Ų
- H-bond donors
- 4
- H-bond acceptors
- 12
- Rotatable bonds
- 7
- Heavy atoms
- 36
SMILES CN(C1=C(C=CC=N1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)C4)S(=O)(=O)C.Cl
Computed descriptors from PubChem (CID 16222312), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il