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Chemical structure of PF-573228

GC11107

PF-573228

Also known as 6-[[4-[(3-methylsulfonylphenyl)methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]-3,4-dihydro-1H-quinolin-2-one

ATP-competitive FAK inhibitor

ChemicalCAS869288-64-2MW491.49FormulaC22H20F3N5O3S
CAS number
869288-64-2
Molecular weight
491.49
Formula
C22H20F3N5O3S
Solubility
≥ 166·6mg/mL in DMSO
InChIKey
HESLKTSGTIBHJU-UHFFFAOYSA-N
Catalogue number
GC11107
Brand
GLPBIO
Computed properties PubChem CID 11612883 · XLogP 3.2 · TPSA 121 Ų · H-bond donors 3
XLogP
3.2
TPSA
121 Ų
H-bond donors
3
H-bond acceptors
10
Rotatable bonds
6
Heavy atoms
34

SMILES CS(=O)(=O)C1=CC=CC(=C1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)CC4

Computed descriptors from PubChem (CID 11612883), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.