GC11917
PF-543
Also known as [(2R)-1-[[4-[[3-(benzenesulfonylmethyl)-5-methylphenoxy]methyl]phenyl]methyl]pyrrolidin-2-yl]methanol
PF-543 is a potent, selective, reversible, and sphingosine-competitive inhibitor of SphK1 with an IC50 value of 2nM and a Ki value of 3·6 nM
ChemicalCAS1415562-82-1MW465.6FormulaC27H31NO4S
- CAS number
- 1415562-82-1
- Molecular weight
- 465.6
- Formula
- C27H31NO4S
- Solubility
- ≥ 23·3 mg/mL in DMSO, ≥ 51 mg/mL in EtOH with ultrasonic and warming
- InChIKey
- NPUXORBZRBIOMQ-RUZDIDTESA-N
- Catalogue number
- GC11917
- Brand
- GLPBIO
Computed properties PubChem CID 66577038 · XLogP 4.2 · TPSA 75.2 Ų · H-bond donors 1
- XLogP
- 4.2
- TPSA
- 75.2 Ų
- H-bond donors
- 1
- H-bond acceptors
- 5
- Rotatable bonds
- 9
- Heavy atoms
- 33
SMILES CC1=CC(=CC(=C1)OCC2=CC=C(C=C2)CN3CCC[C@@H]3CO)CS(=O)(=O)C4=CC=CC=C4
Computed descriptors from PubChem (CID 66577038), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il