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Chemical structure of VX-661

GC14920

VX-661

Also known as 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)indol-5-yl]cyclopropane-1-carboxamide

VX-661 (VX-661) is a second F508del CFTR corrector and help CFTR protein reach the cell surface

ChemicalCAS1152311-62-0MW520.5FormulaC26H27F3N2O6
CAS number
1152311-62-0
Molecular weight
520.5
Formula
C26H27F3N2O6
Solubility
≥ 21·8mg/mL in DMSO
InChIKey
MJUVRTYWUMPBTR-MRXNPFEDSA-N
Catalogue number
GC14920
Brand
GLPBIO
Computed properties PubChem CID 46199646 · XLogP 2.9 · TPSA 113 Ų · H-bond donors 4
XLogP
2.9
TPSA
113 Ų
H-bond donors
4
H-bond acceptors
9
Rotatable bonds
8
Heavy atoms
37

SMILES CC(C)(CO)C1=CC2=CC(=C(C=C2N1C[C@H](CO)O)F)NC(=O)C3(CC3)C4=CC5=C(C=C4)OC(O5)(F)F

Computed descriptors from PubChem (CID 46199646), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.