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Chemical structure of GDC-0623

GC14247

GDC-0623

Also known as 5-(2-fluoro-4-iodoanilino)-N-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide

MEK1 inhibitor, potent and ATP-uncompetitive

ChemicalCAS1168091-68-6MW456.21FormulaC16H14FIN4O3
CAS number
1168091-68-6
Molecular weight
456.21
Formula
C16H14FIN4O3
Solubility
≥ 16·85mg/mL in DMSO
InChIKey
RFWVETIZUQEJEF-UHFFFAOYSA-N
Catalogue number
GC14247
Brand
GLPBIO
Computed properties PubChem CID 42642654 · XLogP 3.7 · TPSA 87.9 Ų · H-bond donors 3
XLogP
3.7
TPSA
87.9 Ų
H-bond donors
3
H-bond acceptors
6
Rotatable bonds
6
Heavy atoms
25

SMILES C1=CC(=C(C=C1I)F)NC2=C(C=CC3=CN=CN32)C(=O)NOCCO

Computed descriptors from PubChem (CID 42642654), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.