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Chemical structure of Enasidenib

GC13147

Enasidenib

Also listed as AG-221 (Enasidenib)

AG-221 (Enasidenib) is an oral, potent, reversible, selective inhibitor of the IDH2 mutant enzymes, with IC50s of 100 and 400 nM against IDH2R140Q and IDH2R172K, respectively

ChemicalCAS1446502-11-9MW473.37FormulaC19H17F6N7O
CAS number
1446502-11-9
Molecular weight
473.37
Formula
C19H17F6N7O
Solubility
≥ 47·3mg/mL in DMSO
InChIKey
DYLUUSLLRIQKOE-UHFFFAOYSA-N
Catalogue number
GC13147
Brand
GLPBIO
Computed properties PubChem CID 89683805 · XLogP 3.5 · TPSA 109 Ų · H-bond donors 3
XLogP
3.5
TPSA
109 Ų
H-bond donors
3
H-bond acceptors
14
Rotatable bonds
6
Heavy atoms
33

SMILES CC(C)(CNC1=NC(=NC(=N1)C2=NC(=CC=C2)C(F)(F)F)NC3=CC(=NC=C3)C(F)(F)F)O

Computed descriptors from PubChem (CID 89683805), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.