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Chemical structure of PF-5190457

GC31478

PF-5190457

Also known as 2-(2-methylimidazo[2,1-b][1,3]thiazol-6-yl)-1-[2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone

PF-5190457 (PF-05190457) is a potent and selective ghrelin receptor inverse agonist with a pKi of 8·36

ChemicalCAS1334782-79-4MW512.67FormulaC29H32N6OS
CAS number
1334782-79-4
Molecular weight
512.67
Formula
C29H32N6OS
Solubility
DMSO： 250 mg/mL (487·64 mM)
InChIKey
ZIUDADZJCKGWKR-AREMUKBSSA-N
Catalogue number
GC31478
Brand
GLPBIO
Computed properties PubChem CID 58438464 · XLogP 4.4 · TPSA 94.9 Ų · H-bond donors 0
XLogP
4.4
TPSA
94.9 Ų
H-bond donors
0
H-bond acceptors
6
Rotatable bonds
4
Heavy atoms
37

SMILES CC1=CC(=NC=N1)C2=CC3=C(C=C2)[C@@H](CC3)N4CC5(C4)CCN(CC5)C(=O)CC6=CN7C=C(SC7=N6)C

Computed descriptors from PubChem (CID 58438464), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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