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Chemical structure of Ipatasertib

GC11214

Ipatasertib

Also listed as GDC-0068 (RG7440)

GDC-0068 (RG7440, Ipatasertib) is a novel highly selective ATP-competitive pan-Akt inhibitor that inhibits all three isoforms of Akt1, Akt2, and Akt3 at an IC50 of 5,18,8 nM, respectively

ChemicalCAS1001264-89-6MW458FormulaC24H32ClN5O2
CAS number
1001264-89-6
Molecular weight
458
Formula
C24H32ClN5O2
Solubility
≥ 22·9mg/mL in DMSO
InChIKey
GRZXWCHAXNAUHY-NSISKUIASA-N
Catalogue number
GC11214
Brand
GLPBIO
Computed properties PubChem CID 24788740 · XLogP 2.5 · TPSA 81.6 Ų · H-bond donors 2
XLogP
2.5
TPSA
81.6 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
6
Heavy atoms
32

SMILES C[C@@H]1C[C@H](C2=C1C(=NC=N2)N3CCN(CC3)C(=O)[C@H](CNC(C)C)C4=CC=C(C=C4)Cl)O

Computed descriptors from PubChem (CID 24788740), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.