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Chemical structure of LD003

GC91569

LD003

Also known as 4-O-[2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 1-O-[(9E,12E)-octadeca-9,12-dienyl] butanedioate

LD003 is a lipid prodrug form of the synthetic glucocorticoid dexamethasone that has been used in the formation of lipid nanoparticles (LNPs) for siRNA and mRNA delivery in vivo

ChemicalCAS2102449-40-9MW741FormulaC44H65FO8
CAS number
2102449-40-9
Molecular weight
741
Formula
C44H65FO8
Solubility
Ethanol： Soluble： ≥10 mg/ml
InChIKey
BSDBWIPACPNDCK-IFQFFTQCSA-N
Catalogue number
GC91569
Brand
GLPBIO
Computed properties PubChem CID 172913490 · XLogP 9.6 · TPSA 127 Ų · H-bond donors 2
XLogP
9.6
TPSA
127 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
23
Heavy atoms
53

SMILES CCCCC/C=C/C/C=C/CCCCCCCCOC(=O)CCC(=O)OCC(=O)[C@]1([C@@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)C)O

Computed descriptors from PubChem (CID 172913490), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.