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Chemical structure of GSK_WRN3

GC75772

GSK_WRN3

Also known as 6-cyclohexyl-N-[(3R)-1,1-dioxo-2,3-dihydrothiophen-3-yl]-5-hydroxy-2-oxo-1H-pyridine-3-carboxamide

GSK_WRN3 is a selective inhibitor of WRN protease (IC50 = 8·6 μM)

ChemicalCAS2923009-50-9MW352.41FormulaC16H20N2O5S
CAS number
2923009-50-9
Molecular weight
352.41
Formula
C16H20N2O5S
Solubility
DMSO： 100 mg/mL (283·76 mM; Need ultrasonic)
InChIKey
NVIXFLSBGMVBNO-LLVKDONJSA-N
Catalogue number
GC75772
Brand
GLPBIO
Computed properties PubChem CID 171391446 · XLogP 0.6 · TPSA 121 Ų · H-bond donors 3
XLogP
0.6
TPSA
121 Ų
H-bond donors
3
H-bond acceptors
5
Rotatable bonds
3
Heavy atoms
24

SMILES C1CCC(CC1)C2=C(C=C(C(=O)N2)C(=O)N[C@H]3CS(=O)(=O)C=C3)O

Computed descriptors from PubChem (CID 171391446), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.