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Chemical structure of GSK-F1

GC65309

GSK-F1

Also known as 5-[2-amino-4-oxo-3-[2-(trifluoromethyl)phenyl]quinazolin-6-yl]-N-(2,4-difluorophenyl)-2-methoxypyridine-3-sulfonamide

GSK-F1 (Compound F1) is an orally active PI4KA inhibitor with pIC50 values of 8·0, 5·9, 5·8, 5·9, 5·9 and 6·4 against PI4KA, PI4KB, PI3KA, PI3KB, PI3KG and PI3KD, respectively

ChemicalCAS1402345-92-9MW603.52FormulaC27H18F5N5O4S
CAS number
1402345-92-9
Molecular weight
603.52
Formula
C27H18F5N5O4S
Solubility
DMSO ： 125 mg/mL (207·12 mM; Need ultrasonic)
InChIKey
MSRFVAYVUUHQCN-UHFFFAOYSA-N
Catalogue number
GC65309
Brand
GLPBIO
Computed properties PubChem CID 57406702 · XLogP 4.3 · TPSA 135 Ų · H-bond donors 2
XLogP
4.3
TPSA
135 Ų
H-bond donors
2
H-bond acceptors
12
Rotatable bonds
6
Heavy atoms
42

SMILES COC1=C(C=C(C=N1)C2=CC3=C(C=C2)N=C(N(C3=O)C4=CC=CC=C4C(F)(F)F)N)S(=O)(=O)NC5=C(C=C(C=C5)F)F

Computed descriptors from PubChem (CID 57406702), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.