GC75745
PROTAC EGFR degrader 9
Also known as N-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-4-yl]-7-[4-[4-[[4-(1-ethylsulfonylindol-3-yl)-5-(trifluoromethyl)pyrimidin-2-yl]amino]phenyl]piperazin-1-yl]heptanamide
PROTAC EGFR degrader 9 (Compound C6) is an orally active CRBN-based PROTAC EGFR degrader
ChemicalCAS2992670-33-2MW899.98FormulaC45H48F3N9O6S
- CAS number
- 2992670-33-2
- Molecular weight
- 899.98
- Formula
- C45H48F3N9O6S
- Solubility
- DMSO： 100 mg/mL (111·11 mM; Need ultrasonic)
- InChIKey
- NFLKKMOHWZTOPF-UHFFFAOYSA-N
- Catalogue number
- GC75745
- Brand
- GLPBIO
Computed properties PubChem CID 171713887 · XLogP 5.4 · TPSA 187 Ų · H-bond donors 3
- XLogP
- 5.4
- TPSA
- 187 Ų
- H-bond donors
- 3
- H-bond acceptors
- 14
- Rotatable bonds
- 15
- Heavy atoms
- 64
SMILES CCS(=O)(=O)N1C=C(C2=CC=CC=C21)C3=NC(=NC=C3C(F)(F)F)NC4=CC=C(C=C4)N5CCN(CC5)CCCCCCC(=O)NC6=CC=CC7=C6CN(C7=O)C8CCC(=O)NC8=O
Computed descriptors from PubChem (CID 171713887), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il