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Chemical structure of PROTAC EGFR degrader 8

GC73506

PROTAC EGFR degrader 8

Also known as 2-[[5-chloro-2-[4-[4-[2-[4-[4-[(2,6-dioxopiperidin-3-yl)amino]phenyl]piperazin-1-yl]acetyl]piperazin-1-yl]-2-methoxyanilino]pyrimidin-4-yl]amino]-N-methylbenzamide

PROTAC EGFR degrader 8 (T-184) is a PROTAC EGFR degrader

ChemicalCAS2925923-46-0MW796.32FormulaC40H46ClN11O5
CAS number
2925923-46-0
Molecular weight
796.32
Formula
C40H46ClN11O5
Solubility
DMSO : 100 mg/mL (125·58 mM; ultrasonic and warming and heat to 60°C)
InChIKey
YDHBIZKMLPNNQN-UHFFFAOYSA-N
Catalogue number
GC73506
Brand
GLPBIO
Computed properties PubChem CID 168476135 · XLogP 4.6 · TPSA 176 Ų · H-bond donors 5
XLogP
4.6
TPSA
176 Ų
H-bond donors
5
H-bond acceptors
13
Rotatable bonds
12
Heavy atoms
57

SMILES CNC(=O)C1=CC=CC=C1NC2=NC(=NC=C2Cl)NC3=C(C=C(C=C3)N4CCN(CC4)C(=O)CN5CCN(CC5)C6=CC=C(C=C6)NC7CCC(=O)NC7=O)OC

Computed descriptors from PubChem (CID 168476135), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.