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Chemical structure of KPT-251

GC74959

KPT-251

Also known as 2-[(Z)-2-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]ethenyl]-1,3,4-oxadiazole

KPT-251 is an orally active chromosome region maintenance 1 protein (CRM1) inhibitor

ChemicalCAS1388841-50-6MW375.23FormulaC14H7F6N5O
CAS number
1388841-50-6
Molecular weight
375.23
Formula
C14H7F6N5O
Solubility
DMSO: 100 mg/mL (266·50 mM; ultrasonic and warming and heat to 60°C)
InChIKey
LDFXTRYMMZGKIC-UPHRSURJSA-N
Catalogue number
GC74959
Brand
GLPBIO
Computed properties PubChem CID 57519758 · XLogP 3.4 · TPSA 69.6 Ų · H-bond donors 0
XLogP
3.4
TPSA
69.6 Ų
H-bond donors
0
H-bond acceptors
11
Rotatable bonds
3
Heavy atoms
26

SMILES C1=C(C=C(C=C1C(F)(F)F)C(F)(F)F)C2=NN(C=N2)/C=C\C3=NN=CO3

Computed descriptors from PubChem (CID 57519758), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.