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Chemical structure of KPT-185

GC14517

KPT-185

Also known as propan-2-yl (Z)-3-[3-[3-methoxy-5-(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]prop-2-enoate

CRM1 inhibitor,selective and irrversible

ChemicalCAS1333151-73-7MW355.31FormulaC16H16F3N3O3
CAS number
1333151-73-7
Molecular weight
355.31
Formula
C16H16F3N3O3
Solubility
≥ 17·8mg/mL in DMSO
InChIKey
NLNGWFLRRRYNIL-PLNGDYQASA-N
Catalogue number
GC14517
Brand
GLPBIO
Computed properties PubChem CID 53495165 · XLogP 3.4 · TPSA 66.2 Ų · H-bond donors 0
XLogP
3.4
TPSA
66.2 Ų
H-bond donors
0
H-bond acceptors
8
Rotatable bonds
6
Heavy atoms
25

SMILES CC(C)OC(=O)/C=C\N1C=NC(=N1)C2=CC(=CC(=C2)OC)C(F)(F)F

Computed descriptors from PubChem (CID 53495165), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.