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Chemical structure of AZ31

GC74860

AZ31

Also known as 6-[6-(methoxymethyl)-3-pyridinyl]-4-[[(1S)-1-(oxan-4-yl)ethyl]amino]quinoline-3-carboxamide

AZ31 is a a potent, highly selective, and orally active ATM inhibitor with an IC50 of ＜1·2 nM for ATM enzyme, and an IC50 of 46 nM for ATM in cell

ChemicalCAS2088113-98-6MW420.5FormulaC24H28N4O3
CAS number
2088113-98-6
Molecular weight
420.5
Formula
C24H28N4O3
Solubility
DMSO： 100 mg/mL (237·81 mM; Need ultrasonic)
InChIKey
DISRGUXSEDBDDN-HNNXBMFYSA-N
Catalogue number
GC74860
Brand
GLPBIO
Computed properties PubChem CID 134694318 · XLogP 2.9 · TPSA 99.4 Ų · H-bond donors 2
XLogP
2.9
TPSA
99.4 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
7
Heavy atoms
31

SMILES C[C@@H](C1CCOCC1)NC2=C3C=C(C=CC3=NC=C2C(=O)N)C4=CN=C(C=C4)COC

Computed descriptors from PubChem (CID 134694318), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.