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Chemical structure of AZ2

GC62335

AZ2

Also known as N-[5-[2-[(1S)-1-cyclopropylethyl]-7-methyl-1-oxo-3H-isoindol-5-yl]-4-methyl-1,3-thiazol-2-yl]acetamide

AZ2 is a highly selective PI3Kγ inhibitor (The pIC50 value for PI3Kγ is 9·3)

ChemicalCAS2231760-33-9MW369.48FormulaC20H23N3O2S
CAS number
2231760-33-9
Molecular weight
369.48
Formula
C20H23N3O2S
Solubility
DMSO ： 50 mg/mL (135·33 mM; Need ultrasonic)
InChIKey
CNCRCDLWUGCPSJ-LBPRGKRZSA-N
Catalogue number
GC62335
Brand
GLPBIO
Computed properties PubChem CID 134163708 · XLogP 3.1 · TPSA 90.5 Ų · H-bond donors 1
XLogP
3.1
TPSA
90.5 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
4
Heavy atoms
26

SMILES CC1=CC(=CC2=C1C(=O)N(C2)[C@@H](C)C3CC3)C4=C(N=C(S4)NC(=O)C)C

Computed descriptors from PubChem (CID 134163708), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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