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Chemical structure of EPZ011989 hydrochloride

GC74088

EPZ011989 hydrochloride

Also known as N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-3-[ethyl-[4-[2-methoxyethyl(methyl)amino]cyclohexyl]amino]-2-methyl-5-(3-morpholin-4-ylprop-1-ynyl)benzamide;hydrochloride

EPZ011989 drochloride is a potent and orally active Zeste Homolog 2 (EZH2) inhibitor, with a Ki value of <3 nM

ChemicalCAS2095432-26-9MW642.27FormulaC35H52ClN5O4
CAS number
2095432-26-9
Molecular weight
642.27
Formula
C35H52ClN5O4
Solubility
DMSO : 100 mg/mL (155·70 mM; Need ultrasonic)
InChIKey
LHRBDVKQGXCMQN-UHFFFAOYSA-N
Catalogue number
GC74088
Brand
GLPBIO
Computed properties PubChem CID 129896818 · TPSA 86.4 Ų · H-bond donors 3 · H-bond acceptors 7
TPSA
86.4 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
12
Heavy atoms
45

SMILES CCN(C1CCC(CC1)N(C)CCOC)C2=CC(=CC(=C2C)C(=O)NCC3=C(C=C(NC3=O)C)C)C#CCN4CCOCC4.Cl

Computed descriptors from PubChem (CID 129896818), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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