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Chemical structure of EPZ011989

GC19141

EPZ011989

Also known as N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-3-[ethyl-[4-[2-methoxyethyl(methyl)amino]cyclohexyl]amino]-2-methyl-5-(3-morpholin-4-ylprop-1-ynyl)benzamide

EPZ011989 is a potent, selective orally bioavailable EZH2 inhibitor with Ki 3000-fold selectivity over other HMTase

ChemicalCAS1598383-40-4MW605.81FormulaC35H51N5O4
CAS number
1598383-40-4
Molecular weight
605.81
Formula
C35H51N5O4
Solubility
DMSO ： ≥ 33 mg/mL (54·47 mM)
InChIKey
XQFINGFCBFHOPE-UHFFFAOYSA-N
Catalogue number
GC19141
Brand
GLPBIO
Computed properties PubChem CID 73670548 · XLogP 3.8 · TPSA 86.4 Ų · H-bond donors 2
XLogP
3.8
TPSA
86.4 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
12
Heavy atoms
44

SMILES CCN(C1CCC(CC1)N(C)CCOC)C2=CC(=CC(=C2C)C(=O)NCC3=C(C=C(NC3=O)C)C)C#CCN4CCOCC4

Computed descriptors from PubChem (CID 73670548), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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