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Chemical structure of BLU0588

GC73517

BLU0588

Also known as N-[(1R,2R)-2-pyrrolidin-1-yl-2,3-dihydro-1H-inden-1-yl]-6-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyridine-3-carboxamide

BLU0588 is an orally active, potent and selective PRKACA (protein kinase cAMP-activated catalytic subunit alpha) kinase inhibitor, with an IC50 of 1 nM and dissociation constant (Kd) of 4 nM

ChemicalCAS2810747-78-3MW423.51FormulaC26H25N5O
CAS number
2810747-78-3
Molecular weight
423.51
Formula
C26H25N5O
Solubility
DMSO ： 83·33 mg/mL (196·76 mM; ultrasonic and warming and heat to 60°C)
InChIKey
YXSWSKFLTNJZEO-DNQXCXABSA-N
Catalogue number
GC73517
Brand
GLPBIO
Computed properties PubChem CID 164603520 · XLogP 3.3 · TPSA 73.9 Ų · H-bond donors 2
XLogP
3.3
TPSA
73.9 Ų
H-bond donors
2
H-bond acceptors
4
Rotatable bonds
4
Heavy atoms
32

SMILES C1CCN(C1)[C@@H]2CC3=CC=CC=C3[C@H]2NC(=O)C4=CN=C(C=C4)C5=C6C=CNC6=NC=C5

Computed descriptors from PubChem (CID 164603520), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.