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Chemical structure of PRMT5-IN-29

GC73445

PRMT5-IN-29

Also known as (2S,3S,4R,5R)-2-[(1R)-1-(3,4-dichlorophenyl)-1-hydroxyethyl]-5-[6-(methoxyamino)purin-9-yl]oxolane-3,4-diol;hydrochloride

PRMT5-IN-29 is a potent and orally active PRMT5 Inhibitor with an IC50 of 1·5 μΜ

ChemicalCAS2242788-69-6MW492.74FormulaC18H20Cl3N5O5
CAS number
2242788-69-6
Molecular weight
492.74
Formula
C18H20Cl3N5O5
Solubility
DMSO ： 130 mg/mL (263·83 mM; Need ultrasonic)
InChIKey
QMVIGLXONQUBTJ-LBQFNWRTSA-N
Catalogue number
GC73445
Brand
GLPBIO
Computed properties PubChem CID 155169689 · TPSA 135 Ų · H-bond donors 5 · H-bond acceptors 9
TPSA
135 Ų
H-bond donors
5
H-bond acceptors
9
Rotatable bonds
5
Heavy atoms
31

SMILES C[C@]([C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)NOC)O)O)(C4=CC(=C(C=C4)Cl)Cl)O.Cl

Computed descriptors from PubChem (CID 155169689), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.