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Chemical structure of CBP/p300-IN-20

GC73365

CBP/p300-IN-20

Also known as (2R,4R)-1-[1-(4-chlorophenyl)-3,3-difluorocyclobutanecarbonyl]-4-fluoro-N-(1H-pyrazolo[4,5-b]pyridin-5-yl)pyrrolidine-2-carboxamide

CBP/p300-IN-20 is a potent and selective p300/CBP inhibitor, with a pIC50 of 10·1 for p300

ChemicalCAS2999742-92-4MW477.87FormulaC22H19ClF3N5O2
CAS number
2999742-92-4
Molecular weight
477.87
Formula
C22H19ClF3N5O2
Solubility
DMSO ： 200 mg/mL (418·52 mM; Need ultrasonic)
InChIKey
YWMDIJGVLFEWKQ-RHSMWYFYSA-N
Catalogue number
GC73365
Brand
GLPBIO
Computed properties PubChem CID 167312228 · XLogP 3.4 · TPSA 91 Ų · H-bond donors 2
XLogP
3.4
TPSA
91 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
4
Heavy atoms
33

SMILES C1[C@H](CN([C@H]1C(=O)NC2=NC3=C(C=C2)NN=C3)C(=O)C4(CC(C4)(F)F)C5=CC=C(C=C5)Cl)F

Computed descriptors from PubChem (CID 167312228), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.