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Chemical structure of TH470

GC73353

TH470

Also known as N-[2-[benzyl-[4-(phenylsulfamoyl)benzoyl]amino]ethyl]-2-(2-methylpropanoylamino)-1,3-thiazole-5-carboxamide

TH470 is a highly selective LIMK1/2 (LIM kinase1/2) inhibitor (LIMK1 IC50=9·8 nM; LIMK2 IC50=13 nM), and can be used in orphan disease research

ChemicalCAS2834739-51-2MW605.73FormulaC30H31N5O5S2
CAS number
2834739-51-2
Molecular weight
605.73
Formula
C30H31N5O5S2
Solubility
DMSO ： 100 mg/mL (165·09 mM; Need ultrasonic)
InChIKey
YVPYJSSYGACUSE-UHFFFAOYSA-N
Catalogue number
GC73353
Brand
GLPBIO
Computed properties PubChem CID 162369728 · XLogP 4.3 · TPSA 174 Ų · H-bond donors 3
XLogP
4.3
TPSA
174 Ų
H-bond donors
3
H-bond acceptors
8
Rotatable bonds
12
Heavy atoms
42

SMILES CC(C)C(=O)NC1=NC=C(S1)C(=O)NCCN(CC2=CC=CC=C2)C(=O)C3=CC=C(C=C3)S(=O)(=O)NC4=CC=CC=C4

Computed descriptors from PubChem (CID 162369728), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.