GC37775
TH287 hydrochloride
Also known as 6-(2,3-dichlorophenyl)-4-N-methylpyrimidine-2,4-diamine;hydrochloride
TH287 hydrochloride is a potent and selective inhibitor of MTH1, with an IC50 of 0·8 nM· TH287 hydrochloride is highly selective towards MTH1, with no relevant inhibition of MTH2, NUDT5, NUDT12, NUDT14, NUDT16, dCTPase, dUTPase and ITPA at 100 μM· TH287 hydrochloride could act as a chemotherapeutic agent for cancer research
ChemicalCAS1638211-05-8MW305.59FormulaC11H11Cl3N4
- CAS number
- 1638211-05-8
- Molecular weight
- 305.59
- Formula
- C11H11Cl3N4
- Solubility
- Soluble in DMSO
- InChIKey
- YBLIJWDQSUDCJU-UHFFFAOYSA-N
- Catalogue number
- GC37775
- Brand
- GLPBIO
Computed properties PubChem CID 91826506 · TPSA 63.8 Ų · H-bond donors 3 · H-bond acceptors 4
- TPSA
- 63.8 Ų
- H-bond donors
- 3
- H-bond acceptors
- 4
- Rotatable bonds
- 2
- Heavy atoms
- 18
SMILES CNC1=NC(=NC(=C1)C2=C(C(=CC=C2)Cl)Cl)N.Cl
Computed descriptors from PubChem (CID 91826506), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il