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Chemical structure of YAP-TEAD-IN-2

GC73349

YAP-TEAD-IN-2

Also known as 2-[(2S)-2-(aminomethyl)-5-chloro-2-phenyl-3H-1-benzofuran-4-yl]-3-fluoro-4-(2-methoxyethoxy)benzamide

YAP-TEAD-IN-2 (compound 6) is a potent YAP-TEAD PPI (protein-protein interaction) inhibitor with IC50 is 2·7 nM

ChemicalCAS2714432-83-2MW470.92FormulaC25H24ClFN2O4
CAS number
2714432-83-2
Molecular weight
470.92
Formula
C25H24ClFN2O4
Solubility
DMSO ： 100 mg/mL (212·35 mM; Need ultrasonic)
InChIKey
DMOHFURXRRTVGP-RUZDIDTESA-N
Catalogue number
GC73349
Brand
GLPBIO
Computed properties PubChem CID 157852210 · XLogP 3.4 · TPSA 96.8 Ų · H-bond donors 2
XLogP
3.4
TPSA
96.8 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
8
Heavy atoms
33

SMILES COCCOC1=C(C(=C(C=C1)C(=O)N)C2=C(C=CC3=C2C[C@@](O3)(CN)C4=CC=CC=C4)Cl)F

Computed descriptors from PubChem (CID 157852210), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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