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Chemical structure of YAP/TAZ inhibitor-1

GC19912

YAP/TAZ inhibitor-1

Also known as (NE)-N-[2-(4,4-dimethylcyclohexyl)sulfonyl-7-[4-(1-phenylethyl)piperazin-1-yl]sulfonylfluoren-9-ylidene]hydroxylamine

YAP/TAZ inhibitor-1 is a YAP/TAZ inhibitor extracted from patent WO2017058716A1, Compound 1, has an IC50 of <0·100 μΜ in firefly luciferase assay

ChemicalCAS2093565-23-0MW621.81FormulaC33H39N3O5S2
CAS number
2093565-23-0
Molecular weight
621.81
Formula
C33H39N3O5S2
Solubility
DMSO ： 62·5 mg/mL (100·51 mM; Need ultrasonic)
InChIKey
MYVLNSCWZUAUMQ-NWBJSICCSA-N
Catalogue number
GC19912
Brand
GLPBIO
Computed properties PubChem CID 138377547 · XLogP 5.9 · TPSA 124 Ų · H-bond donors 1
XLogP
5.9
TPSA
124 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
6
Heavy atoms
43

SMILES CC(C1=CC=CC=C1)N2CCN(CC2)S(=O)(=O)C3=CC\4=C(C=C3)C5=C(/C4=N\O)C=C(C=C5)S(=O)(=O)C6CCC(CC6)(C)C

Computed descriptors from PubChem (CID 138377547), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.