
GC65131
YAP/TAZ inhibitor-2
Also known as 2-fluoro-1-[3-[3-[4-(trifluoromethyl)phenyl]pyrazolo[5,4-b]pyridin-1-yl]azetidin-1-yl]prop-2-en-1-one
YAP/TAZ inhibitor-2 is a potent and orally active TEAD-YAP/TAZ inhibitor with an EC50 value of 3 nM· YAP/TAZ inhibitor-2 shows anti-proliferative activity· YAP/TAZ inhibitor-2 shows antitumor activity
ChemicalCAS2762617-31-0MW390.33FormulaC19H14F4N4O
- CAS number
- 2762617-31-0
- Molecular weight
- 390.33
- Formula
- C19H14F4N4O
- Solubility
- DMSO : 100 mg/mL (256·19 mM; Need ultrasonic)
- InChIKey
- GTRCXQAYBUYBBE-UHFFFAOYSA-N
- Catalogue number
- GC65131
- Brand
- GLPBIO
Computed properties PubChem CID 164885340 · XLogP 3.5 · TPSA 51 Ų · H-bond donors 0
- XLogP
- 3.5
- TPSA
- 51 Ų
- H-bond donors
- 0
- H-bond acceptors
- 7
- Rotatable bonds
- 3
- Heavy atoms
- 28
SMILES C=C(C(=O)N1CC(C1)N2C3=C(C=CC=N3)C(=N2)C4=CC=C(C=C4)C(F)(F)F)F
Computed descriptors from PubChem (CID 164885340), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il