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Chemical structure of USP8-IN-2

GC73283

USP8-IN-2

Also known as 1-(5-chloro-2-methoxyphenyl)-3-[1-[6-(trifluoromethyl)-2-pyridinyl]piperidin-4-yl]thiourea

USP8-IN-2 (Compd U52) is a deubiquitinase USP8 inhibitor with an IC50 value of 6·0 μM

ChemicalCAS2477651-11-7MW444.9FormulaC19H20ClF3N4OS
CAS number
2477651-11-7
Molecular weight
444.9
Formula
C19H20ClF3N4OS
Solubility
DMSO ： 100 mg/mL (224·77 mM; Need ultrasonic)
InChIKey
XKLBIJSKEVHKCM-UHFFFAOYSA-N
Catalogue number
GC73283
Brand
GLPBIO
Computed properties PubChem CID 152406100 · XLogP 4.7 · TPSA 81.5 Ų · H-bond donors 2
XLogP
4.7
TPSA
81.5 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
4
Heavy atoms
29

SMILES COC1=C(C=C(C=C1)Cl)NC(=S)NC2CCN(CC2)C3=CC=CC(=N3)C(F)(F)F

Computed descriptors from PubChem (CID 152406100), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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