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Chemical structure of USP7-IN-8

GC62377

USP7-IN-8

Also known as 4-[6-amino-4-ethyl-5-(4-hydroxyphenyl)-3-pyridinyl]-N-methylbenzamide

USP7-IN-8 (example 81) is a selective ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 of 1·4 μM in an Ub-Rho110 assay· USP7-IN-8 shows no activity against USP47 and USP5· USP7-IN-8 has anticancer effects

ChemicalCAS2009273-60-1MW347.41FormulaC21H21N3O2
CAS number
2009273-60-1
Molecular weight
347.41
Formula
C21H21N3O2
Solubility
DMSO ： 83·33 mg/mL (239·86 mM; Need ultrasonic)
InChIKey
GUXGBQOCJOOOFS-UHFFFAOYSA-N
Catalogue number
GC62377
Brand
GLPBIO
Computed properties PubChem CID 122531799 · XLogP 3.5 · TPSA 88.2 Ų · H-bond donors 3
XLogP
3.5
TPSA
88.2 Ų
H-bond donors
3
H-bond acceptors
4
Rotatable bonds
4
Heavy atoms
26

SMILES CCC1=C(C(=NC=C1C2=CC=C(C=C2)C(=O)NC)N)C3=CC=C(C=C3)O

Computed descriptors from PubChem (CID 122531799), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.